Post-Traumatic Stress Disorder (PTSD) and addiction are two separate conditions, but they may often occur together. Their coexistence can form a complex cycle that can make recovery even more challenging. PTSD alone is a mental health condition that is triggered by past traumatic experiences, such as combat, assault, natural disasters, or serious accidents. Whereas addiction involves the compulsive use of substances despite their harmful consequences.
As per the U.S. Department of Veterans Affairs, over 46% of people with PTSD also struggle with some form of substance use disorder. [1] Because of this strong link between PTSD and addiction, it is essential to understand how trauma and substance abuse are related to each other. Only after properly understanding the relationship between the two can long-term recovery be possible.
Why PTSD and Addiction Often Co-Exist
People with PTSD often have difficulty coping with their condition. Therefore, they frequently turn to alcohol or drugs as a way to deal with painful memories, anxiety, and emotional numbness.
Initially, these substances may offer temporary relief by helping individuals sleep better or feel calmer. However, use of these substances for long periods can further worsen the symptoms of PTSD and lead to dependence.
Common symptoms of PTSD that may contribute to addiction tendencies include:
- Intrusive thoughts or flashbacks that trigger intense stress
- Insomnia and nightmares leading to fatigue and irritability
- Hyperarousal, or being constantly on edge
- Emotional numbness, where individuals feel detached from others
- Avoidance behaviors, where people steer clear of reminders of the trauma

How Addiction Affects PTSD Symptoms
Drugs and alcohol may provide short-term comfort. However, they can also disrupt the brain’s natural ability to manage stress and emotions. Over time, addiction can:
- Increase anxiety and depression
- Worsen memory and concentration problems
- Trigger more frequent flashbacks or nightmares
- Interfere with sleep patterns
- Reduce impulse control and emotional regulation
PTSD and addiction can have a vicious cycle, with PTSD driving substance use and substance use worsening PTSD. For instance, alcohol is a depressant that can heighten depressive feelings and guilt. Whereas stimulants like cocaine can intensify hyperarousal and panic attacks in PTSD.
Shared Brain Mechanisms Between PTSD and Addiction
The regions of the brain affected are very similar in PTSD and addiction. In particular, the amygdala, hippocampus, and prefrontal cortex may be affected. [2]
- The amygdala is the part of the brain that governs fear and emotional memory. In PTSD, the amygdala may become overactive. This may lead to heightened fear responses.
- The prefrontal cortex is the region in the brain that is responsible for making decisions and controlling impulses. It may become less active in PTSD. This can make it harder to resist substance cravings.
- The hippocampus can help distinguish between safe and dangerous situations. It is often smaller in people with PTSD. Therefore, it can lead to persistent feelings of threat.
This overlap between PTSD and addiction means that trauma not only alters emotional regulation but also increases susceptibility to addictive behaviors.
The Cycle of PTSD and Addiction
- Trauma Exposure: A traumatic event occurs in the life of the individual.
- Onset of PTSD Symptoms: The event triggers anxiety, flashbacks, and insomnia.
- Self-Medication: To cope with the symptoms, the person uses alcohol or drugs to ease emotional pain.
- Short-Term Relief: The substances provide temporary relief from the symptoms.
- Dependence Develops: Long-term use of the substances makes the brain rely on the substance.
- Worsening PTSD: Withdrawal and emotional instability intensify the symptoms of PTSD.
In order to break this cycle, an integrated treatment plan is essential that targets both PTSD and substance use simultaneously.
Effective Treatment Approaches for PTSD and Addiction
An effective recovery strategy should address both conditions together, and not separately. If only one condition is treated without the other, then it can often lead to relapse. Some evidence-based treatment options for PTSD include:
Trauma-Focused Therapy
Some approaches, such as Cognitive Behavioural Therapy (CBT) and Prolonged Exposure (PE) can help people reframe the traumatic experiences. This can help reduce avoidance behaviors and regain control over the emotional response. Such therapies are particularly effective when they are combined with substance use treatment.
Eye Movement Desensitization and Reprocessing (EMDR)
EMDR is a method to help people reprocess the traumatic memories in a safe and structured environment. Research has shown that EMDR can be effective in reducing PTSD symptoms and lowering the urge to self-medicate. [3]
Medication-Assisted Treatment (MAT)
For people struggling with addiction, medications such as naltrexone, buprenorphine, or disulfiram can help manage the cravings and symptoms of withdrawal. Some people may benefit from antidepressants such as SSRIs (e.g., sertraline, paroxetine) as they may help treat anxiety and depression related to PTSD.
Integrated Dual Diagnosis Programs
Some rehabilitation centers often offer treatment for dual diagnosis to address both PTSD and addiction in tandem. These programs may include:
- Cognitive Behavioral Therapy (CBT)
- Group counseling
- Relapse prevention planning
- Mindfulness and stress management techniques
PTSD and Addiction Recovery: What to Expect
Recovering from PTSD and addiction is not always straightforward. It is a gradual process of healing both the mind and body. Most people with PTSD benefit from a combination of medical supervision, therapy, and community support.
Addiciton recovery often involves detox and stabilization in the early phase. This is followed by trauma-focused therapy once the withdrawal symptoms have subsided. With time, people can rebuild trust, regain emotional balance, and learn healthier coping strategies.
However, relapse may still occur, but this doesn’t mean failure. It is an opportunity to adjust the treatment plan and strengthen resilience. It is crucial to have ongoing therapy and social support for maintaining long-term sobriety and emotional health.
Final Thoughts
PTSD and addiction are deeply intertwined with each other. Trauma can alter the brain chemistry and emotional regulation. This makes people more vulnerable to substance misuse, whereas addiction can worsen PTSD symptoms.
However, with the right addiction treatment, therapy, and social support, it is entirely possible to achieve long-term recovery.
References
| ↑1 | Sonya Norman, PhD, Terrell Hicks, PhD, Alexandra Klein, PhD, and Jessica Hamblen, PhD. Treatment of Co-Occurring PTSD and Substance Use Disorder in VA |
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| ↑2 | Shin, Lisa M., Scott L. Rauch, and Roger K. Pitman. “Amygdala, medial prefrontal cortex, and hippocampal function in PTSD.” Annals of the New York Academy of Sciences 1071.1 (2006): 67-79. |
| ↑3 | Lortye, Sera, et al. “Effectiveness of treating post‐traumatic stress disorder in patients with co‐occurring substance use disorder with prolonged exposure, eye movement desensitization and reprocessing or imagery rescripting: A randomized controlled trial.” Addiction (2025). |
